Monday, December 29, 2025

Understanding Addiction Through the Brain

The International Conference on Neurology and Neuroscience 2026 will host an impactful keynote by Meera Vaswani, All India Institute of Medical Sciences (AIIMS), India. Her in-person keynote presentation, Neurobiology of Addiction,” presents addiction as a chronic brain disorder driven by neurobiological and genetic mechanisms rather than a failure of willpower.


🔑 Key Insights from the Keynote

  • Addiction Reframed as a Brain Disease
    Long-term substance exposure alters neural circuits regulating reward, motivation, emotion, and self-control.

  • Role of Dopamine and Reward Pathways
    Dysregulated dopamine signaling within the mesolimbic system reinforces compulsive drug-seeking behavior.

  • The Three-Stage Addiction Cycle
    Binge/intoxication, withdrawal with negative emotional states, and craving due to impaired executive control.

  • From Impulsivity to Compulsivity
    Early pleasure-driven use progresses to habitual and compulsive behavior despite harmful consequences.

  • Genetic and Molecular Vulnerability
    Specific genes and molecular pathways influence addiction risk, relapse, and treatment response.

  • Clinical and Translational Impact
    Advances support precision medicine approaches for individualized addiction prevention and therapy.

  • Global Research Perspective
    Integrates international and population-based studies highlighting cultural and genetic influences.



🌐 Why This Keynote Is Important

This presentation connects neuroscience, psychiatry, and genetics to explain the biological roots of addiction and offers valuable insights for clinicians, researchers, and healthcare professionals focused on brain health and substance use disorders.


📅 Conference Snapshot

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