Tuesday, December 9, 2025

Dr. Zhifei Fu to Present Breakthrough in Red Fluorescent Protein Technology

The International Conference on Neurology and Neuroscience, scheduled for March 23–25, 2026, will feature a remarkable in-person presentation by Dr. Zhifei Fu from Fujian Medical University, China. His cutting-edge research introduces a new era of high-stability red fluorescent proteins designed to power the next generation of advanced microscopy.

Title: A highly stable monomeric red fluorescent protein for advanced microscopy


🚀 Introducing mScarlet3-H: A New Benchmark in Red Fluorescent Proteins

Dr. Fu’s presentation will unveil mScarlet3-H, an exceptionally stable monomeric red fluorescent protein engineered for demanding imaging applications. This new variant promises to elevate the accuracy, clarity, and durability of fluorescence-based microscopy used in neuroscience and cellular biology.


🔍 Key Takeaways from the Presentation

  • Ultra-stable structural design revealed by 1.5 Å resolution analysis.
  • Exceptional resistance to heat, chaotropic agents, and oxidative conditions—ideal for complex imaging workflows.
  • Minimal photobleaching, allowing continuous 3D SIM tracking of mitochondrial dynamics for up to two hours.
  • Breakthrough performance in CLEM, enabling clearer visualization of diverse cellular organelles.
  • Rapid tissue clearing capability, achieving whole-organ transparency in under 24 hours.
  • Optimized compatibility with STED microscopy, supporting high-contrast dual-color imaging.
  • Validated superiority over leading RFPs, making it a preferred choice for multiplexed imaging across model organisms.
  • Applicable to zebrafish, mice, and plant systems, extending its utility beyond traditional cell culture studies.

👨🔬 About Dr. Fu: A Leader in Super-Resolution and correlative Imaging

Dr. Zhifei Fu leads a forward-thinking research group focused on pushing the boundaries of super-resolution correlative light and electron microscopy (SR-CLEM). His team’s work includes:

  • Designing next-generation fluorescent proteins
  • Refining super-resolution image reconstruction algorithms
  • Advancing CLEM and volume electron microscopy workflows
  • Publishing influential work in Nature Methods, Nano Letters, JoVE, Sleep, and Journal of Cell Biology

Currently, his lab is using SR-CLEM and VEM to map neural circuits with unprecedented detail.



📅 Join Us at the Neurology & Neuroscience Conference 2026

Event Name: International Conference on Neurology and Neuroscience
Dates: March 23–25, 2026
Format: Hybrid (Singapore & Online)
Website:
https://neurocareconference.com/
Submit Abstract:
https://neurocareconference.com/abstract-submission
Register Here:
https://neurocareconference.com/register
Contact Email: neurology@mathewsconference.com
Phone: +1 (312) 462-4448
WhatsApp: +1 (424) 377-0967

Connect with the event community on X: https://x.com/NeuroCareEvent


📣 Be Part of This Transformative Scientific Gathering

Don’t miss the opportunity to learn how advancements in fluorescent protein engineering are shaping the future of neuroscience research and high-resolution imaging technologies.


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